About the Program :)
















 

Howard L. Liber
hliber@colosate.edu
Department of Environmental and Radiological Health Sciences
Colorado State University
Website:http://www.cvmbs.colostate.edu/erhs/faculty/liber/liber.htm


Currently Funded Projects:

Molecular Mechanisms of Radiation-Induced Genomic Instability in Human Cells

Technical Abstracts:

Publications:

Zhang, Y., Zhou, J., Held, K.D., Redmond, R.W., Prise, K.M., and Liber, H.L. (2008) Deficiencies of double-strand break repair factors and effects on mutagenesis in directly [gamma]-irradiated and medium-mediated bystander human lymphoblastoid cells. Radiation Research 169(2):197-206.

Zhang, Y., Zhou, J.Q., Cao, X.F., Zhang, Q., Lim, C.U.K., Ullrich, R.L., Bailey, S.M., and Liber, H.L. (2007) Partial deficiency of DNA-PKcs increases ionizing radiation-induced mutagenesis and telomere instability in human cells. Cancer Letters 250(1):63-73.

Schwartz, J.L., Jordan, R., Slovic, J., Moruzzi, A., Liber, H.L. (2006) Chronic low dose radiation effects on radiation sensitivity, (adaptive response, low dose hypersensitivity) and genomic instability in TK6 cells. Environmental and Molecular Mutagenesis 47(6):434

Zhang, Y., Lim, C.U.K., Williams, E.S., Zhou, J., Zhang, Q., Fox, M.H., Bailey, S.M., and Liber, H.L. (2005) NBS1 knockdown by small interfering RNA increases ionizing radiation mutagenesis and telomere association in human cells. Cancer Research 65(13):5544-5553.

Schwartz, J.L., Jordan, R., Evans, H.H., Lenarczyk, M., and Liber, H.L. (2003) The TP53 dependence of radiation-induced chromosome instability in human lymphoblastoid cells. Radiation Research 159(6):730–736.

Peng, Y., Zhang, Q., Nagasawa, H., Okayasu, R., Liber, H.L., and Bedford, J.S. (2002) Silencing expression of the catalytic subunit of DNA-dependent protein kinase by small interfering RNA sensitizes human cells for radiation-induced chromosome damage, cell killing and mutation. Cancer Research 62:6400-6404.

Chuang, Y.-Y. and Liber, H.L. (1996) Effects of cell cycle position on ionizing radiation mutagenesis. I. Quantitative assays of two genetic loci in a human lymphoblastoid cell line. Radiation Research 146:494-500.

 



                   
                   
                   
 

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