Michael C. Joiner
Wayne State University

Past Project:

Mechanisms of Enhanced Cell Killing at Low Doses: Implications for Radiation Risk

Technical Abstracts:

• 2002 Workshop:

  Mechanisms of Enhanced Cell Killing at Low Doses: Implications for Radiation Risk. Project ID: 69981.
  Johnston, P.J., Cann, N.E.,. Mitchell, C.R., Short, S., Marples, B., Scott, S.D., Joiner, M.C. and Wilson, G.D.

• 2001 Workshop:

  Mechanisms of Enhanced Cell Killing at Low Doses: Implications for Radiation Risk.
  Marples, B., Johnston, P.J., Scott, S.D., Wilson, G.D. and Joiner, M.C.

• 1999 Workshop:

Mechanisms of Enhanced Cell Killing at Low Doses: Implications for Radiation Risk.
Joiner, M.C., Johnston, P.J., Marples, B., Scott, S.D. and Wilson, G.D.

Publications:

Chalmers, A., Johnston, P., Woodcock, M., Phil, M., Joiner, M., and Marples, B. (2004) PARP-1, PARP-2, and the cellular response to low doses of ionizing radiation. Int. J. Radiation Oncology Biol. Phys., 58(2): 410-419.

Harney, J., Short, S.C., Shah, N., Joiner, M., and Saunders, M.I. (2004) Low dose hyper-radiosensitivity in metastatic tumors. Int. J. Radiation Oncology Biol. Phys. 59(4):1190-1195.

Harney, J., Shah, N., Short, S., Daley, F., Groom, N., Wilson, G.D., Joiner, M.C., Saunders, M.I. (2004) The evaluation of low dose hyper-radiosensitivity in normal human skin. Radiotherapy and Oncology, 70: 319-329.

Joiner, M. (2004) New frontiers or red herrings in radiation oncology. The Lancet Oncology 5:10.

Marples, B., Wouters, B.G., Collis, S.J., Chalmers, A.J., and Joiner, M.C. (2004) Low-dose hyper-radiosensitivity: A consequence of ineffective cell cycle arrest of radiation-damage G2-phase cells. Radiation Research 161:247-255.

Coleman, C.N., Stone, H.B., Alexander, G.A., Barcellos-Hoff, M.H., Bedford, J.S., Bristow, R.G., Dynlacht, J.R., Fuks, Z., Gorelic, L.S., Hill, R.P., Joiner, M.C., Liu, F-F., McBride, W.H., Mckenna, W.G., Powell, S.N., Robbins, M.E.C., Rockwell, S., Schiff, P.B., Shaw, E.G., Siemann, D.W., Travis, E.L., Wallner, P.E., Wong, R.S.L., and Zeman, E.M. (2003) Education and training for radiation scientists: Radiation Research Program and American Society of Therapeutic Radiology and Oncology Workshop, Bethesda, Maryland, May 12-14, 2003. Radiation Research 160:729-737

Marples, B., Wouters, B.G., and Joiner, M.C. (2003) An association between the radiation-induced arrest of G2-phase cells and low-dose hyper-radiosensitivity: A plausible underlying mechanism? Radiation Research 160:38-45.

Mothersill, C., Seymour, C.B. and Joiner, M.C. (2002) Relationship between radiation-induced low-dose hypersensitivity and the bystander effect. Radiation Research 157:526-532.

Marples, B., Cann, N.E., Mitchell, C.R., Johnston, P.J., Joiner, M.C. (2002) Evidence for the involvement of DNA-dependent protein kinase in the phenomena of low dose hyper-radiosensitivity and increased radioresistance. Int. J. Radiat. Biol. 78(12):1139-1149.

Joiner, M.C., Marples, B., Lambin, P., Short, S., and Turesson, I. (2001) Low-dose hypersensitivity: current status and possible mechanisms. Int. J. of Radiation Oncology Biol. Phys. 49(2):379-389.

Joiner, M.C., Lambin, P., Malaise, E.P., Robson, T., Arrand, J.E., Skov, K.A., and Marples, B. (1996) Hypersensitivity to very-low single radiation doses: Its relationship to the adaptive response and induced radioresistance. Mutation Research 358:171-183.

Joiner, M.C., Lambin, P., Malaise, E.P., Robson, T., Arrand, J.E., Skov, K.A., and Marples, B. (1996) Hypersensitivity to very-low single radiation doses: Its relationship to the adaptive response and induced radioresistance. Mutation Research 358:171-183.