Low Dose Suppression of Neoplastic Transformation In vitro, abstract, description.

• 2006 Workshop:
  The Effect of Dose-Rate on Radiation-Induced Neoplastic Transformation In Vitro by Low Doses of Low LET Radiation
  Elmore, E., Lao, X-Y., Kapadia, R., and Redpath, J.L.
  
  
  
• 2005 Workshop:
  
  Low Dose Studies of Neoplastic Transformation In vitro by Low-LET Radiations
  Redpath, J.L., Lao, X.-Y., Kapadia, R., and Elmore, E.
  
  
• 2003 Workshop:
  Neoplastic Transformation In vitro Following Exposure to Low Doses of Low-LET Radiation
  Redpath, J.L., Lao, X.-Y., Pant, M., Ko, S., Christie, C., Taylor, T., and Elmore, E.

• 2002 Workshop:
  Dose Dependence of Radiation-Induced Adaptive Response Against Neoplastic Transformation In vitro
  Redpath, J.L., Liang, D., Taylor, T.H., James, C., and Elmore, E.
  
  
• 1999 Workshop:
  Adaptive Response Against Spontaneous Neoplastic Transformation In vitro Induced by Ionizing Radiation
  Redpath, J.L., Elmore, E., and Taylor, T.

Elmore, E., Lao, X.Y., Kapadia, R., Giedzinski, E., Limoli, C., and Redpath, J.L. (2008) Low doses of very low-dose-rate low-LET radiation suppress radiation-induced neoplastic transformation in vitro and induce an adaptive response. Radiation Research 169(3):311-318.

Wang, X.Q., Stanbridge, E.J., Lao, X., Cai, Q., Fan, S.T., and Redpath, J.L. (2007) p53-dependent Chk1 phosphorylation is required for maintenance of prolonged G(2) arrest. Radiation Research 168(6):706-715.

Elmore, E., Jain, A., Siddiqui, S., Tohidian, N., Meyskens, F.L., Steele, V., and Redpath, J.L. (2007) Development and characteristics of a human cell assay for screening agents for melanoma prevention. Melanoma Research 17(1):42-50.

Schollnberger, H., Mitchel, R.E.J., Redpath, J.L., Crawford-Brown, D.J., and Hofmann, W. (2007) ) Detrimental and protective bystander effects: A model approach. Radiation Research 168(5):614-626.

Elmore, E., Jain, A., Siddiqui, S., Tohidian, N., Meyskens, F.L., Steele, V. E., and Redpath, J.L. (2007) Development and characteristics of a human cell assay for screening agents for melanoma prevention. Melanoma Research 17:42-50.

Redpath, J.L. (2007) In vitro radiation-induced neoplastic transformation: Suppressive effects at low doses. In: Extended Abstracts Radiation Research: State of the science twenty years after Chernobyl. Radiation Research 167(3):345-346.

Redpath, J.L. and Mitchel, R.E.J. (2006) Enhanced biological effectiveness of low energy X-rays and implications for the UK breast screening programme - Correspondence. British J. of Radiology 79(946):854-855.

Redpath, J.L. (2006) Suppression of neoplastic transformation in vitro by low doses of low LET radiation. Dose-Response 4(4):302-308.

Wang, X.Q., Redpath, J.L., Fan. S.T., and Stanbridge, E.J. (2006) ATR dependent activation of Chk2. Journal of Cellular Physiology 208:613-619.

Deng, W-P., Chao, M-W., Lai, W-F., Sun, C., Chung, C-Y., Wu, C-C., Lin, I-H., Hwang, J-J., Wu., C-H., Chiu, W-T., Chen, C-Y., Redpath, J.L. (2006) Correction of malignant behavior of tumor cells by traditional Chinese herb medicine through a restoration of p53. Cancer Letters 233:315-327.

Elmore, E., Lao, X-Y., Kapadia, R., and Redpath, J.L. (2006) The effect of dose rate in radiation-induced neoplastic transformation in vitro by low doses of low-LET radiation. Radiation Research 166:832-838.

Redpath, J.L. (2006) Radiation-induced neoplastic transformation in vitro, hormesis, and risk assessment. Environmental and Molecular Mutagenesis 47(6):403.

Ko, M., Lao, X-Y., Kapadia, R., Elmore, E. and Redpath, J.L . (2006) Neoplastic transformation in vitro by low doss of ionizing radiation: Role of adaptive response and bystander effects. Mutation Research 597(1-2):11-17.

Mendonca, M.S., Farrington, D.L., Mayhugh, B.M., Qin, Y., Temples, T., Comerford, K., Chakrabarti, R., Zainabadi, K., Redpath, J.L., Stanbridge, E.J., and Srivatsan, E.S. (2004) Homozygous deletions within the 11q13 cervical cancer tumor-suppressor locus in radiation-induced, neoplastically transformed human hybrid cells. Genes, Chromosomes & Cancer 39:277-287.

Elmore, E., Lao, X.Y., Ko, M., Rightnar, S., Nelson, G., and Redpath, J.L. (2005) Neoplastic transformation in vitro induced by low doses of 232 MeV protons. International J. of Radiation Biology 81(4):291-297.

Redpath, J.L. (2005) Nonlinear response for neoplastic transformation following low doses of low-LET radiation. Nonlinearity in Biology, Toxicology and Medicine 3:113-124.

Redpath, J.L. (2004) Radiation-induced neoplastic transformation in vitro: Evidence for a protective effect at low doses of low-LET radiation. Cancer and Metastasis Reviews 23:333-339.

Ko, S.J., Liao, X.-Y., Molloi, S., Elomore, E., and Redpath, J.L. (2004) Neoplastic transformation in vitro after exposure to low doses of mammographic-energy X-rays: Quantitative and mechanistic aspects. Radiation Research 162:646-654.

Lio, Y.-C., Schild, D., Brenneman, M.A., Redpath, J.L., and Chen, D.J. (2004) Human Rad51C deficiency destabilizes XRCC3, impairs recombination, and radiosensitizes S/G2-phase cells. J. of Biological Chemistry 279(40):42313-42320.

Redpath, J.L. (2004) Suppression of neoplastic tranformation in vitro by low doses of low-LET radiation. In: The 14th Pacific Basin Nuclear Conference, Honolulu, Hawaii.

Pant, M.C., Liao, X.-Y., Lu, Q., Molloi, S., Slmore, E., and Redpath, J.L. (2003) Mechanisms of suppression of neoplastic transformation in vitro by low doses of low-LET radiation. Carcinogenesis 24(12):1961-1965.

Redpath, J.L., Lu, Q., Lao, X., Molloi, S., and Elmore, E. (2003) Low doses of diagnostic energy X-rays protect against neoplastic transformation in vitro. International J. of Radiation Biology 79(4):235-240.

Redpath, J.L., Short, S.C., Woodcock, M., and Johnston, P.J. (2003) Low-dose reduction in transformation frequency compared to un-irradiated controls: The role of hyper-radiosensitivity to cell death. Radiation Research 159:422-436.

DeSimone, J.N., Bengtsson, U., Wang, X.Q., Lao, X.Y., Redpath, J.L., and Stanbridge, E.J. (2002) Complexity of the mechanisms of initiation and maintenance of DNA damage-induced G2-arrest and subsequent G1 phase arrest: TP53-dependent and TP53-independent roles. Radiation Research 159(1):72-85.

Redpath, J.L., Bengtsson, U., DeSimone, J., Lao, X., Wang, X., and Stanbridge, E.J. (2002) Sticky anaphase aberrations after G2-phase arrest of gamma-irradiated human skin fibroblasts: TP53 independence of formation and TP53 dependence of consequences. Radiation Research 159(1):57-71.

Redpath, J.L., Liang, D., Taylor, T.H., Christie, C., and Elmore, E. (2001) The shape of the dose-response curve for radiation-induced neoplastic transformation in vitro: Evidence for an adaptive response against neoplastic transformation at low doses of low-LET radiation. Radiation Research 156:700-707.

Redpath, J.L. and Guiterrez, M. (2001) Kinetics of induction of reactive oxygen species during the post-irradiation expression of neoplastic transformation in vitro. International J. of Radiation Biology 77(11):1081-1085.

Redpath, J.L., Liang, D., Taylor, T.H., Christie, C., and Elmore, E. (2001) The shape of the dose-response curve for radiation-induced transformation in vivo: Evidence for an adaptive response against neoplastic transformation at low doses of low-LET radiation. Radiation Rearch 156:700-701.

Ehring, G.R., Antoniono, R.J., and Redpath, J.L. (1998) Gap junction expression following UVC-induced neoplastic transformation in human hybrid cell lines. Carcinogensis 19(12):2085-2093.

Redpath, J.L. and Antoniono, R.J. (1998) Induction of an adaptive response against spontaneous neoplastic transformation in vitro by low-dose gamma radiation. Radiation Research 149:517-520.

Sun, C., Redpath, J.L., Coleman, M., and Stanbridge, E.J. (1988) Further studies of the radiation-induced expression of a tumor-specific antigen in human cell hybrids. Radiation Research 114:84-93.

Redpath, J.L., Sun, C., Coleman, M., and Stanbridge, E.J. (1987) Neoplastic transformation of human hybrid cells by y radiation: A quantitative assay. Radiation Research 110:468-472.