Principle Investigators for the Low Dose Radiation Research Program

John H. Miller
Washington State University Tri-Cities
E-mail: jhmiller@tricity.wsu.edu
Website: http://www.tricity.wsu.edu/htmls/eecs/cs/faculty/residentfaculty.html#JohnMiller

Currently Funded Projects:

Models for the Generation of Bystander Effects by Low Doses of Ionizing Radiation

Technical Abstracts:

2006 Workshop:
Application of Ab-Initio Quantum and Classical Molecular Dynamics Simulations to Study Clustered DNA Damage
Miller, J.H., Ernst, M.B., Haranczyh, M., Douali, L., Gutowski, M., and Dupuis, M.

Identification and Characterization of Factors Involved in Delayed Effects of Radiation
Springer, D.L., Peters, J.S., Daly, D.S., Moore, R.J., Jin, S., Johnson, R.E., Morgan, W.F., and Miller, J.H.
2005 Workshop:
Radiation-iInduced Protein Release: A Source of Bystander Signaling?
Miller, J.H., Jin, S., Opresko, L., and Springer, D.
2003 Workshop:
Models for Radiation-Induced Release of Cytokines by Autocrine-Cell Systems: Implications for Bystander Effects
Miller, J.H., Zheng. F., Resat, H., Opresko, L., Springer, D., and Wiley H.S.

2002 Workshop:
Are Autocrine Loops a Mechanism for Bystander Effects?
Miller, J.H., Zheng, F., and Shvartsman, S.Y.
2001 Workshop:
Low-LET Microbeam Dosimetry.
Wilson, W.E., Miller, J.H., Lynch, D.J., Wei, K., and Kurtulus, A.
Low-LET Microbeam Dosimetry.
Wilson, W.E., Miller, J.H., Lynch, D.J., Wei, K., and Kurtulus, A.
1999 Workshop:
A Novel, Spatially Resolved Cell Irradiator to Study Bystander and Adaptive Responses to Low-LET Radiation.
Kimmel, G.A., Thrall, B.D., Miller, J.H., and Strom, D.J.

Publications:

Miller, J.H., Jin, S., Morgan, W.F., Yang, A., Wan, Y., Aypar, U., Peters, J.S., and Springer, D.L. (2008) Profiling mitochondrial proteins in radiation-induced genome-unstable cell lines with persistent oxidative stress by mass spectrometry. Radiation Research 169(6):700-706.

Jin, S., Daly, D.S., Springer, D.L., and Miller, J.H. (2008) The effects of shared peptides on protein quantitation in label-free proteomics by LC/MS/MS. Journal of Proteome Research 7(1):164-169.

Haranczyk, M., Miller, J.H., and Gutowski, M. (2007) Differences in electrostatic potential around DNA fragments containing adenine and 8-oxo-adenine: An analysis based on regular cylindrical projection. Journal of Molecular Graphics & Modelling 26(1):282-289.

Braby, L., Brenner, D., Cherubini, R., Cremer, T., Durante, M., Geard, C. Kobayashi, K., Miller, J.H., Prise, K., and Taucher-Scholz, G. (2006) Session 1. Microbeam probes of cellular radiation response. In: Extended Abstracts: Proceedings of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response.Radiation Research 166:652-653.

Miller, J.H., Ginovska, B., and Wilson, W.E. (2006) Session 7. Is the plasma membrane a target for generation signals to bystanders? Proceedings of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response.Radiation Research 166:685.

Ahram, M., Strittmatter, E. F., Monroe, M. E., Adkins, J. N., Hunter, J. C., Miller, J. H., and Springer, D. L. (2005) Identification of shed proteins from Chinese hamster ovary cells: application of statistical confidence using human and mouse protein databases. Proteomics 5:1815-1826.

Lynch, D.J., Wilson, W.E., Batdorf, M.T., Sowa Resat, M.B., Kimmel, G.A., and Miller, J.H. (2005) Monte Carlo simulation of the spatial distribution of energy deposition for an electron microbeam. Radiation Research 163(4):468–472.

Miller, J.H. , Aceves-Gaona, A., Ernst, M.B., Haranczyk, M., Gutowski, M., Vorpagel, E.R., and Dupuis, M. (2005) Structure and energetics of clustered damage sites. Radiation Research 164(4):582-585.

Sowa, M.B., Murphy, M.K., Miller, J.H., McDonald, J.C., Strom, D.J., and Kimmel, G.A. (2005) A variable-energy electron microbeam: A unique modality for targeted low-LET radiation. Radiation Research 164:695-700.

Springer, D.L., Ahram, M., Adkins, J.N., Kathmann, L.E., and Miller, J.H. (2005) Characterization of medium conditioned by irradiated cells using proteome-wide, high-throughput mass spectrometry. Radiation Research 164:651-654.

Miller, J.H., Batdorf, M.T., Lynch, D.J., Lewis, R.R., and Wilson, W.E. (2004) Microdosimetry of electron microbeams. Radiation Research 162:474-479.

Wilson, W.E., Miller, J.H., Lynch, D.J., Lewis, R.R., and Batdorf, M. (2004) Anaylsis of low-energy electron track structure in liquid water. Radiation Research 161:591-596.

Miller, J.H., and Zheng, F. (2004) Large-scale simulations of cellular signaling processes. Parallel Computing 30(9-10):1137-1149.

Miller, J.H., Fan-Chiang, C.-C.P., Straatsma, T.P., and Kennedy, M.A. (2003) 8-Oxyoguanine enhances bending of DNA that favors binding to glycosylases. J. American Chemical Society 125:6331-6336.

Miller, J.H., Wilson, W.E., Lynch, D.J., Wei, K., Kurtulus, A., and Trease, H.E. (2002) Low-LET microbeam dosimetry. Radiation Research 158:377-378.

Miller, J.H., Wilson, W.E., Lynch, D.J., Resat, M., and Trease, H.E. (2001) Computational dosimetry for electron microbeams: Monte Carlo track simulation combined with confocal microscopy. Radiation Research 156:438-439.

Miller, J.H., Sowa-Resat, M., Metting, N.F., Wei, K., Lynch, D.J., and Wilson, W.E. (2000) Monte Carlo simulation of single-cell irradiation by an electron microbeam. Radiat. Environ. Biophys. 39:173-177.

Wilson, W.E., Lynch, D.J., Wei, K., and Miller, J.H. (2000). Microdosimetry for low-dose low-LET selected cell irradiations. In: Proceedings: Radiation protection for our national priorities: Medicine, the environment and the legacy, Sept. 17-21, 2000, Spokane, Washington.