About the Low Dose Radiation Research Program

	Newly Funded Projects 03-07 Low Dose Basic Research Identification of Mouse Genetic Susceptibility to Radiation Carcinogenesis An expression Array Strategy to Identify Mouse Strain-Specific DNA Damage Response Pathways in Mammary Tissue Allan Balmain abalmain@cc.ucsf.edu University of California, San Francisco Multidimensional Analysis of Human Epithelial Cell Response to Low Dose Radiation An expression Array Strategy to Identify Mouse Strain-Specific DNA Damage Response Pathways in Mammary Tissue Mary Helen Barcellos-Hoff mhbarcellos-hoff@lbl.gov Lawrence Berkeley National Laboratory Transgenerational Radiation Genetics: A feasibility Study for the Use of the Japanese Medaka to Investigate Adaptive Responses and Genomic Instability Joel S. Bedford jbedford@colostate.edu Colorado State University Is Increased Low-Dose Radiosensitivity Associated with Increased Transgenerational Germline Mutation Radiosensitivity? Studies of Bystander Effects in 3-D Tissue Systems Using a Low-LET Microbeam mFISH Measurements of Chromosomal Aberrations in Individuals Exposed in Utero to Gamma-Ray Doses from 5-20 cGy David Brenner djb3@columbia.edu Columbia University Cellular and Molecular Studies of Radio-Adaptive Responses Judith Campisi JCampisi@lbl.gov Lawrence Berkeley National Laboratory Low Dose Radiation Damage and Radioprotection in the Vertebrate Embryo William Dynan wdynan@mail.mcg.edu Medical College of Georgia Genomic Instability Induced by a Bystander Signal Ed Goodwin goodwin_edwin_h@lanl.gov Los Alamos National Laboratory Individual Genetic Susceptibility Eric Hall ejha1@columbia.edu Columbia University Return to the top A Quantitative Assessment of Bystander Mutagenesis in the Mouse Mammary Gland In vivo Amy Kronenberg a_kronenberg@lbl.gov Lawrence Berkeley National Laboratory Molecular Characterization of the Role of SOD Genes in Mammalian Cellular Response to Low Dose Ionizing Chaun-Yuan Li cyli@radonc.duke.edu Duke University Medical Center Regulation of NF-kB and Mn SOD in Low Dose Radiation Induced Adaptive Responses in Mouse and Human Skin Cells Jian Jian Li jjli@coh.org City of Hope National Medical Center Real-Time Molecular Study of Bystander Effect Using Living Cell Imaging and Nanaparticles Optics Mohan Natarajan natarajan@uthscsa.edu University of Texas Health Science Center Methods for Deriving Gene and Pathway Specific Dose Response Curves from Expression Experiments Using DNA Microarrays David Nelson Loma Linda University Mechanisms(s) of Three-Dimensional Intercellular Signaling in Mammary Epithelial Cells in Response to Low Dose, Low-LET Radiation: Implications for the Radiation-Induced Bystander Effects Lee Opresko lee.opresko@pnl.gov Pacific Northwest National Laboratory Bystander and Adaptive Responses in Tissue Models Exposed to Low Radiation Doses Kevin Prise prise@gci.ac.uk Gray Cancer Institute Low Dose Suppression of Neoplastic Transformation In vitro J. Leslie Redpath jlredpat@uci.edu University of California, Irvine Quantification of Repair of Low-Dose-Induced DNA Double-Strand Breaks in Diploid Human Cells David Schild DSchild@lbl.gov Lawrence Berkeley National Laboratory The Characterization of Genetic Responses to Low Dose Radiation Using a Genome-Wide Insertional Mutagensis Approach Katherine Vallis Katherine.vallis@rmp.uhn.on.ca Princess Margaret Hospital Return to the top BIO-BASED RISK MODELING 03-20 Use of Computational Modeling to Evaluate Hypotheses About the Molecular and Cellular Mechanisms of Bystander Effects Rory Conolly Rconolly@ciit.org Website: http://www.ciit.org/Researchers/rconolly Chemical Institute for Industrial Toxicology Research Triangle Park, NC 27709 Use of a State-Vector Model of Radiation Carcinogenesis to Integrate Information from In vitro, In vivo, Epidemiological and Physiological Studies Douglas Crawford-Brown douglas_crawford-brown@unc.edu Website: http://www.unc.edu/~dcrawfor/doug.htm University of North Carolina Chapel Hill, NC 27599 Biologically-Based Risk Modeling with a Focus on Cellular Repair Mechanisms for Radiation-Induced Damage Robert Goble rgoble@clarku.edu Website: http://www.clarku.edu/departments/idce/faculty/goble.cfm Clark University Worcester, MA 01610 Multi-level Kinetic and Dynamic Biologically Based Risk Models for Low Dose Radiation William Griffith Griffith@u.washington.edu Website: http://depts.washington.edu/chc/riskchar.html University of Washington Seattle, WA 98105 Biologically-Based Multistage Modeling of Radiation Effects William Hazelton hazelton@fhcrc.org Fred Hutchinson Cancer Institute Seattle, WA 98105 Modeling the Interrelations Among Radiation-Induced Bystander Effects, Genomic Instability, and Cancer Rainer Sachs sachs@math.berkeley.edu Website: http://math.berkeley.edu/~sachs/ University of California-Berkeley Berkley, CA 7472 Biological-Based Modeling of Low Dose Radiation Risks Bobby Scott BScott@Lrri.org Website:http://www.lrri.org/staff/directoryofscientists/scott.html Lovelace Respiratory Research Institute Albuquerque, NM 87108 Towards Constructing and Testing a Virtual Tissue Robert Stewart trebor@purdue.edu Website: http://www.healthsciences.purdue.edu/faculty/stewart.html Purdue University West Lafayette, IN 47907-2051 Return to the top

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